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 Cocaine Abuse and Dependence TreatmentThe principles of cocaine rehabilitation are similar to treatment of alcoholism or sedativism. Detoxification is a prerequisite in the treatment of this disorder.Antianxiety DrugsSevere cocaine induced agitation can be treated with diazepam (Valium) 5 to 10 mg every 3 hours IM or PO. Tachyarrhythmias can be treated with propranolol (Inderol) 10 to 20 mg PO every 4 hours.Antidepressant DrugsIn preliminary tests, imipramine and desipramine reduced cocaine euphoria and craving.LithiumLithium has been reported to block cocaine euphoric effects, though recent evidence suggests lithium is effective only in bipolar or cyclothymic patients.Other DrugsVitamin C (0.5 g PO every 6 hours) may increase urinary excretion by acidifying urine.Treatment outcome is affected more by such factors as employment status, family support, and degree of antisocial features than by initial motivation for treatment.It is likely that some heavy cocaine users, like other heavy